![]() ![]() Based on anecdotal evidence that children with acute leukemia worsened if they were given folic acid, he worked on blocking folic acid metabolism. In June 1948, Sidney Farber reported promising results in treatment of early childhood leukemia.The neurologist would go on to describe what is now known as the Brown-Séquard syndrome. In October 1872, a lecture by Charles-Édouard Brown-Séquard was published that proposed the then-revolutionary idea that one cerebral hemisphere can influence both sides of the body.In June 1906, James Homer Wright published an article that described how he stained and studied bone marrow with descriptions of what are now known as megakaryocytes and platelets."Other severe operations have been performed without the knowledge of the patients." "A patient has been rendered completely insensible during an amputation of the thigh, regain consciousness after a short interval," Bigelow wrote. This allowed patients to remain sedated during operations ranging from dental extraction to amputation. ![]()
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